A naturally occurring substance which is produced by the body as a stress response to stroke, alpha-B-crystallin, works to absorb inflammation molecules in the brain to reduce damage. When more of this substance is introduced up to 12 hours after a stroke, it reduces the size of the resulting brain lesions. Experiments were performed on alpha-B-crystallin deprived genetically deprived mice, which showed much improved outcomes for the treated mice versus their control group.
The stuff we use now, TPA, must be administered withing 4.5 hours of the stroke.
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